Current Issue May 2012, Vol. 61, No. 5

Editor-in-Chief

Christos S. Mantzoros, MD, DSc

Christos Mantzoros is Professor of Medicine at Harvard Medical School. He serves as the Chief of Endocrinology, Diabetes and Metabolism at the Boston VA Healthcare System and the Director of the Human Nutrition Unit of the Division of Endocrinology Diabetes and Metabolism at Beth Israel Deaconess Medical Center and the Joslin Diabetes Center.
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Issue Highlights

Review

Metabolic consequences of stress during childhood and adolescence
May 2012(Vol. 61 | No. 5 | Pages 611-619)
Panagiota Pervanidou, George P. Chrousos

Brief Reports

Long-term recovery of β-cell function after partial pancreatectomy in humans
May 2012(Vol. 61 | No. 5 | Pages 620-624)
Bjoern A. Menge, Thomas G.K. Breuer, Peter R. Ritter, Waldemar Uhl, Wolfgang E. Schmidt, Juris J. Meier

ENPP1 K121Q polymorphism and type 2 diabetes mellitus in the Chinese population: a meta-analysis including 11 855 subjects
May 2012(Vol. 61 | No. 5 | Pages 625-633)
Yan-yan Li

The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats
17 May 2012
Danúbia Frasson, Renata Polessi Boschini, Valéria Ernestânia Chaves, Maria Emília Soares Martins dos Santos, Sílvia de Paula Gomes, Rafael Rossi Valentim, Maria Antonieta Rissato Garófalo, Luiz Carlos Carvalho Navegantes, Renato Hélios Migliorini, Isis do Carmo Kettelhut
Abstract: The aim of the present study was to investigate the participation of the sympathetic nervous system (SNS) in the control of glycerol-3-P (G3P) generating pathways in white adipose tissue (WA...
Leptin in congenital or HIV-associated lipodystrophy and metabolic syndrome: A need for more mechanistic studies and large, randomized, placebo-controlled trials
17 May 2012
Joo-Pin Foo, Christos S. Mantzoros
Lipodystrophy is a clinically heterogeneous group of disorders characterized by abnormal adipose tissue metabolism, which is almost always complicated by metabolic derangements. The abnormal adipose t...
Sulfated oxysterol 25HC3S as a therapeutic target of non-alcoholic fatty liver disease
16 May 2012
Ji-Young Cha, Young-Bum Kim
In mammals, triglycerides are predominantly synthesized in the liver by de novo lipogenesis and in turn, exported in the form of very low density lipoprotein (VLDL) particles to adipose and other tiss...
Effects of an intensive behavioral weight loss intervention consisting of caloric restriction with or without physical activity on common carotid artery remodeling in severely obese adults
11 May 2012
Jennifer N. Cooper, Mindy L. Columbus, Kelly J. Shields, Julius Asubonteng, Michelle L. Meyer, Kim Sutton-Tyrrell, Bret H. Goodpaster, James P. DeLany, John M. Jakicic, Emma Barinas-Mitchell
Abstract: Objective: Obesity increases cardiovascular disease risk and adversely affects vascular structure and function. Few studies have evaluated the vascular effects of non-surgical weight reducti...
Caffeic acid phenethyl ester reduces the activation of the nuclear factor κB pathway by high-fat diet-induced obesity in mice
10 May 2012
Rosângela Maria Neves Bezerra, Lucimara Fernanda Veiga, Aline Camila Caetano, Pedro Luiz Rosalen, Maria Esméria Corezola Amaral, Adrianne Christine Palanch, Severino Matias de Alencar
Abstract: Objective: The aim of this study was to investigate the effect of CAPE on the insulin signaling and inflammatory pathway in the liver of mice with high fat diet induced obesity. Material/Met...

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Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C–ι
April 2012 (Vol. 61 | No. 4 | Pages 459-469)
Mini P. Sajan, Sonali Nimal, Stephen Mastorides, Mildred Acevedo-Duncan, C. Ronald Kahn, Alan P. Fields, Ursula Braun, Michael Leitges, Robert V. Farese
The relationship between vitamin D and the renin-angiotensin system in the pathophysiology of hypertension, kidney disease, and diabetes
April 2012 (Vol. 61 | No. 4 | Pages 450-458)
Anand Vaidya, Jonathan S. Williams
Management of type 2 diabetes: evolving strategies for the treatment of patients with type 2 diabetes
January 2011 (Vol. 60 | No. 1 | Pages 1-23)
Ebenezer A. Nyenwe, Terri W. Jerkins, Guillermo E. Umpierrez, Abbas E. Kitabchi
Addition of metformin to exogenous glucagon-like peptide–1 results in increased serum glucagon-like peptide–1 concentrations and greater glucose lowering in type 2 diabetes mellitus
January 2011 (Vol. 60 | No. 1 | Pages 52-56)
Joy Cuthbertson, Steven Patterson, Finbarr P. O'Harte, Patrick M. Bell
Vaspin and visfatin/Nampt are interesting interrelated adipokines playing a role in the pathogenesis of type 2 diabetes mellitus
January 2011 (Vol. 60 | No. 1 | Pages 63-70)
Hala O. El-Mesallamy, Dina H. Kassem, Ebtehal El-Demerdash, Ashraf I. Amin
Effects of lifestyle modification on metabolic parameters and carotid intima-media thickness in patients with type 2 diabetes mellitus
August 2006 (Vol. 55 | No. 8 | Pages 1053-1059)
So Hun Kim, Suk Jeong Lee, Eun Seok Kang, Shinae Kang, Kyu Yeon Hur, Hyun Joo Lee, Chul Woo Ahn, Bong Soo Cha, Ji Soo Yoo, Hyun Chul Lee
Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women
September 2011 (Vol. 60 | No. 9 | Pages 1211-1221)
Elizabeth Sienkiewicz, Faidon Magkos, Konstantinos N. Aronis, Mary Brinkoetter, John P. Chamberland, Sharon Chou, Kalliopi M. Arampatzi, Chuanyun Gao, Anastasia Koniaris, Christos S. Mantzoros

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Acknowledgment to reviewers
Metabolism, Volume 61, Issue 4, April 2012, Pages 599-602

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Free Featured Articles

The relationship between vitamin D and the renin-angiotensin system in the pathophysiology of hypertension, kidney disease, and diabetes
April 2012 (Vol. 61 | No. 4 | Pages 450-458)
Anand Vaidya, Jonathan S. Williams
Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C–ι
April 2012 (Vol. 61 | No. 4 | Pages 459-469)
Mini P. Sajan, Sonali Nimal, Stephen Mastorides, Mildred Acevedo-Duncan, C. Ronald Kahn, Alan P. Fields, Ursula Braun, Michael Leitges, Robert V. Farese
Dietary calcium and body weight: what's the “skinny”?
February 2012 (Vol. 61 | No. 2 | Pages 137-139)
Catherine M. Gordon, Christos S. Mantzoros
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S100A16 mediation of weight gain attenuation induced by dietary calcium
February 2012 (Vol. 61 | No. 2 | Pages 157-163)
Rihua Zhang, Weidong Zhu, Xinli Du, Jing Xin, Yi Xue, Yuanyuan Zhang, Dong Li, Yun Liu

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About Metabolism

Metabolism promotes excellence in research by publishing high-quality original research papers, fast-tracking cutting-edge papers, research brief reports, mini-reviews, and other special articles related to all aspects of human metabolism. Work considered for publication in Metabolism includes studies in humans, animal and cellular models. Work with strong translational potential is prioritized. Metabolism will consider papers for publication in any aspect of translational and clinical metabolic research, including (but not limited to):

Energy Expenditure and Obesity
Metabolic Syndrome and Diabetes
Nutrition, Exercise, and the Environment
Genetics, Proteomics, and Metabolomics
Carbohydrate, Lipid, and Protein Metabolism
Endocrinology and Hypertension
Mineral and Bone Metabolism
Cardiovascular Diseases and Malignancies