Metabolism - Clinical and Experimental
Volume 44, Issue 12 , Pages 1577-1580 , December 1995

Alcoholism abolishes the growth hormone response to sumatriptan administration in man

  • V. Coiro

      Affiliations

    • Corresponding Author InformationAddress reprint requests to V. Coiro, MD, Istituto di Clinica Medica Generale e Terapia Medica, Via A. Gramsci 14-43100 Parma, Italy.
    • ,
  • P.P. Vescovi

Received 22 November 1994 ,Accepted 28 March 1995.

References 

  1. McCann SM, Krulich L. Role of transmitters in control of anterior pituitary hormone release. In:  DeGroot LJ editors. Endocrinology. vol 1:Philadelphia, PA: Saunders; 1989;p. 122–129
  2. Muller EE. Neural control of somatotropic function. Physiol Rev. 1987;67:962–1053
  3. Miki N, Ono M, Shizume K. Evidence that opiatergic and alfa-adrenergic mechanisms stimulate rat growth hormone release via growth hormone-releasing factor (GRF). Endocrinology. 1984;114:1950–1952
  4. Eden S, Eriksson E, Martin JB, et al.  Evidence for a growth hormone releasing factor mediating alfa-adrenergic influence on growth hormone secretion in the rat. Neuroendocrinology. 1981;33:2427
  5. Arnold MA, Fernstrom JD. Administration of antisomatostatin serum to rats reverses the inhibition of pulsatile growth hormone secretion produced by injection of metergoline but not yohimbine. Neuroendocrinology. 1980;31:194–199
  6. Kakucska I, Makara GB. Various putative neurotransmitters affect growth hormone (GH) release in rats with anterolateral hypothalamic deafferentation of the medial basal hypothalamus: Evidence for mediation by a GH-releasing factor. Endocrinology. 1983;113:318–323
  7. Conway S, Richardson L, Speciale S, et al.  Interaction between norepinephrine and serotonin in the neuroendocrine control of growth hormone release in the rat. Endocrinology. 1990;126:1022–1030
  8. De Marinis L, Mancini A, Fiumara C, et al.  Growth hormone response to growth hormone-releasing hormone in early abstinent alcoholic patients. Psychoneuroendocrinology. 1993;18:475–483
  9. Herdman JRE, Delva NJ, Hockney RE, et al.  Neuroendocrine effects of sumatriptan. Pharmacology. 1994;113:561–564
  10. Rolandi E, Franceschini R, Cataldi A, et al.  Endocrine effects of sumatriptan. Lancet. 1992;339:1365
  11. Alba-Roth J, Muller OA, Schopohl J, et al.  Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion. J Clin Endocrinol Metab. 1988;67:1186–1189
  12. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol. 1959;32:50–55
  13. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry. 1960;23:56–62
  14. Schalch DS, Parker ML. A sensitive double antibody immunoassay for human growth hormone in plasma. Nature. 1964;203:1141–1142
  15. Dieguez C, Page MD, Scanlon MF. Growth hormone neuroregulation and its alterations in disease states. Clin Endocrinol (Oxf). 1988;28:109–143
  16. Daoust M, Saligaut C, Chadelaud M, et al.  Attenuation by antidepressant drugs of alcohol intake in rats. Alcohol. 1984;1:379–383
  17. Rockman GE, Amit Z, Brown ZW, et al.  An investigation of the mechanisms of action of the 5-hydroxytryptamine in the suppression of ethanol intake. Neuropharmacology. 1982;21:341–347
  18. Le AD, Khanna JM, Kalant H, et al.  Effect of modification of brain serotonin (5-HT), norepinephrine (NE) and dopamine (DA) on ethanol tolerance. Psychopharmacology. 1981;75:231–235
  19. Linnoila M, Eckardt M, Durcan M, et al.  Interactions of serotonin with ethanol: Clinical and animal studies. Psychopharmacol Bull. 1987;23:452–457
  20. Buczek Y, Tomkins DM, Higgins GA, et al.  Dissociation of serotonergic regulation of anxiety and ethanol self-administration: A study with mCPP. Behav Pharmacol. 1994;5:470–484
  21. Daoust M, Compagnon P, Legrand E, et al.  Ethanol intake and 3H-serotonin. uptake I. A study in fawn-hooded rats. Life Sci. 1991;48:1969–1976
  22. Lee MA, Meltzer HY. Neuroendocrine responses to serotonergic agents in alcoholics. Biol Psychiatry. 1991;30:1017–1030
  23. Terry LC, Martin JB. Evidence for alfa-adrenergic regulation of episodic GH and prolactin secretion in the undisturbed male rat. Endocrinology. 1981;108:1869–1873
  24. Martin JB, Durand D, Gurd W, et al.  Neuropharmacological regulation of episodic growth hormone and prolactin secretion in the rat. Endocrinology. 1978;102:106–113
  25. Florini JR, Prinz PN, Vitiello MV. Somatomedin-C levels in healthy young and old men: Relationship to peak and 24-hour integrated levels of growth hormone. J Gerontol. 1985;40:2–7
  26. Clemmons DR, Van Wyk JJ. Factors controlling blood concentration of somatomedin-C. Clin Endocrinol Metab. 1984;13:113–143
  27. Brambilla F, Zarattini F, Gianelli A, et al.  Plasma opioids in alcoholics after acute alcohol consumption and withdrawal. Acta Psychiatr Scand. 1988;77:63–66
  28. Genazzani AR, Nappi G, Facchinetti F, et al.  Central deficiency of beta-endorphin in alcohol addicts. J Clin Endocrinol Metab. 1982;55:583–586
  29. Vescovi PP, Coiro V, Volpi R, et al.  Plasma beta-endorphin, but not met-enkephalin, levels are abnormal in chronic alcoholics. Alcohol Alcohol. 1992;27:471–475
  30. Rees LH, Bresser GM, Jeffcoate WJ, et al.  Alcohol-induced pseudo-Cushing's syndrome. Lancet. 1977;1:726–728

PII: 0026-0495(95)90078-0

Metabolism - Clinical and Experimental
Volume 44, Issue 12 , Pages 1577-1580 , December 1995

Article Tools