Metabolism - Clinical and Experimental
Volume 44, Issue 8 , Pages 1008-1012 , August 1995

Effect of loop diuretics and nonsteroidal antiinflammatory drugs on thyrotropin release by rat anterior pituitary cells in vitro

  • Chen-Fee Lim

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Chen-Fee Lim, PhD, Ewen Downie Metabolic Unit, Alfred Hospital, Commercial Road, Melbourne, Victoria, Australia, 3181.
    • Ewen Downie Metabolic Unit, Alfred Hospital, Melbourne, Victoria, Australia
    • Department of Medicine, Monash University, Melbourne, Victoria, Australia
    • ,
  • Nicole M. Loidl

      Affiliations

    • Ewen Downie Metabolic Unit, Alfred Hospital, Melbourne, Victoria, Australia
    • Department of Medicine, Monash University, Melbourne, Victoria, Australia
    • ,
  • Jennifer A. Kennedy

      Affiliations

    • Ewen Downie Metabolic Unit, Alfred Hospital, Melbourne, Victoria, Australia
    • Department of Medicine, Monash University, Melbourne, Victoria, Australia
    • ,
  • Duncan J. Topliss

      Affiliations

    • Ewen Downie Metabolic Unit, Alfred Hospital, Melbourne, Victoria, Australia
    • Department of Medicine, Monash University, Melbourne, Victoria, Australia
    • ,
  • Jan R. Stockigt

      Affiliations

    • Ewen Downie Metabolic Unit, Alfred Hospital, Melbourne, Victoria, Australia
    • Department of Medicine, Monash University, Melbourne, Victoria, Australia

Received 27 June 1994 ,Accepted 12 December 1994.

References 

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  2. Taylor R, Hutton C, Weeke J, et al.  Fenclofenac-secondary effects upon the pituitary thyroid axis. Clin Endocrinol (Oxf). 1983;19:683–692
  3. Köhrle J, Fang SL, Yang Y, et al.  Rapid effects of the flavonoid EMD 21388 on serum thyroid hormone binding and thyrotropin regulation in the rat. Endocrinology. 1989;125:532–537
  4. Leuprasitsakul W, Alex S, Fang SL, et al.  Flavonoid administration immediately displaces thyroxine (T4) from serum transthyretin, increases serum free T4, and decreases serum thyrotropin in the rat. Endocrinology. 1990;126:2890–2895
  5. Newnham HH, Hamblin PS, Long F, et al.  Effect of oral furosemide on diagnostic indices of thyroid function. Clin Endocrinol (Oxf). 1987;26:423–431
  6. Evans PJ, Woodhead JS, Weeks I, et al.  Circulating TSH levels measured with an immunochemiluminometric assay in patients taking drugs interfering with biochemical thyroid status. Clin Endocrinol (Oxf). 1987;26:717–721
  7. Everts ME, Docter R, van Buuren JCJ, et al.  Evidence for carrier-mediated uptake of triiodothyronine in cultured anterior pituitary cells of euthyroid rats. Endocrinology. 1993;132:1278–1285
  8. Everts ME, Docter R, Moerings EPMC, et al.  Uptake of thyroxine in cultured anterior pituitary cells of euthyroid rats. Endocrinology. 1994;134:2490–2497
  9. Kennedy JA, Nicolson R, Wellby ML. The effect of oleic acid on the secretion of thyrotropin and growth hormone by cultured rat anterior pituitary cells. J Endocrinol. 1994;143:557–564
  10. Surks MI, Ordene KW, Mann DN, et al.  Diphenylhydantoin inhibits the thyrotropin response to thyrotropin-releasing hormone in man and rat. J Clin Endocrinol Metab. 1983;56:940–945
  11. Mendel CA, Cavalieri RR, Gavin LA, et al.  Thyroxine transport and distribution in Nagase analbuminemic rats. J Clin Invest. 1989;83:143–148
  12. Oosterom R, Verleun T, Lamberts SWJ. Basal and dopamine-inhibited prolactin secretion by anterior pituitary cells: Effects of culture conditions. Mol Cell Endocrinol. 1983;29:197–212
  13. Oosterom R, Verleun T, Zuyderwijk J, et al.  Growth hormone secretion by cultured rat anterior pituitary cells. In: Effects of culture conditions and dexamethasone. ed 2. Endocrinology. 113:1983;p. 735–741
  14. Taylor R, Clark F, Griffiths ID, et al.  Prospective study of effect of fenclofenac on thyroid function tests. Br Med J. 1980;281:911–912
  15. Larsen PR, Silva JE, Kaplan MM. Relationships between circulating and intracellular thyroid hormones: Physiological and clinical implications. Endocr Rev. 1981;2:87–102
  16. Schrey MP, Larsen PR. Evidence for a possible role for Ca++ in the 3,5,3′-triiodothyronine inhibition of thyrotropin releasing hormone-induced secretion of thyrotropin by rat anterior pituitary in vitro. Endocrinology. 1981;108:1690–1696
  17. Ings RM, Stevens LA. Pharmacokinetics and metabolism of diuretics. Drug Metab. 1983;7:57–171
  18. Everts ME, Visser TJ, Moerings EPCM, et al.  Uptake of triiodothyroacetic acid and its effect on thyrotropin secretion in cultured anterior pituitary cells. Endocrinology. 1994;135:2700–2707
  19. Silva JE, Dick TE, Larsen PR. The contribution of local tissue thyroxine monodeiodination to the nuclear 3,5,3′-triiodothyronine in pituitary, liver, and kidney of euthyroid rats. Endocrinology. 1978;103:1196–1207
  20. van Doorn J, van der Heide D, Roelfsema F. Sources and the quantity of 3,5,3′-triiodothyronine in several tissues of the rat. J Clin Invest. 1983;72:1178–1792
  21. Heyma P, Larkins RG, Perry-Keene D, et al.  Thyroid hormone levels and protein binding in patients on long-term diphenylhydantoin treatment. Clin Endocrinol (Oxf). 1977;6:369–376
  22. Liewendahl K, Majuri H, Helenuis T. Thyroid function tests in patients on longer-term treatment with various anticonvulsant drugs. Clin Endocrinol (Oxf). 1978;8:185–191

☆ Supported by a grant from the Alfred Group of Hospitals.

PII: 0026-0495(95)90097-7

Metabolism - Clinical and Experimental
Volume 44, Issue 8 , Pages 1008-1012 , August 1995

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