Metabolism - Clinical and Experimental
Volume 44, Issue 11 , Pages 1384-1390 , November 1995

Relationship between obesity and concentration and composition of low-density lipoprotein subfractions in normoinsulinemic men

Received 17 March 1994 ,Accepted 30 March 1995.

References 

  1. Castelli WP, Garrison RJ, Wilson PWF, et al.  Incidence of coronary heart disease and lipoprotein cholesterol levels. JAMA. 1986;256:2835–2838
  2. Brunzell JD, Sniderman AD, Albers JJ, et al.  Apoproteins B and A-I and coronary artery disease in humans. Arterioscler Thromb. 1984;4:79–83
  3. Miller NE, Hammet F, Saltissi S, et al.  Relation of angiographically defined coronary artery disease to plasma lipoprotein subfractions and apolipoproteins. Br Med J. 1981;282:1741–1744
  4. Salonen JT, Salonen R, Seppänen K, et al.  HDL, HDL2, and HDL3 subfractions, and the risk of acute myocardial infarction. In: A prospective population study in eastern Finnish men. ed 2. Circulation. 84:1991;p. 129–139
  5. Austin MA, Breslow JL, Hennekens CH, et al.  Low-density lipoprotein subclass patterns and risk of myocardial infarction. JAMA. 1988;260:1917–1921
  6. Austin MA, King MC, Vranizan K, et al.  Atherogenic lipoprotein phenotype: A proposed genetic marker for coronary heart disease risk. Circulation. 1990;82:495–506
  7. Nigon F, Lesnik P, Rouis M, et al.  Discrete subspecies of human low density lipoproteins are heterogeneous in their interaction with the cellular LDL receptor. J Lipid Res. 1991;32:1741–1753
  8. Campos H, Genest JJ, Blijlevens E, et al.  Low density lipoprotein particle size and coronary artery disease. Arterioscler Thromb. 1992;12:187–195
  9. Tornvall P, Karpe F, Carlson LA, et al.  Relationships of low density lipoprotein subfractions to angiographically defined coronary artery disease in young survivors of myocardial infarction. Atherosclerosis. 1991;90:67–80
  10. Griffin BA, Freeman DJ, Graeme WT, et al.  Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: Relative contribution of small, dense LDL to coronary heart disease risk. Atherosclerosis. 1994;106:241–253
  11. Manson JE, Stampfer MJ, Hennekens CH, et al.  Body weight and longevity: A reassessment. JAMA. 1987;257:353–358
  12. Hubert HB, Feinleib M, McNamara PM, et al.  Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study. Circulation. 1983;67:968–977
  13. Van Itallie TB. Health implications of overweight and obesity in the United States. Ann Intern Med. 1985;103:983–988
  14. Campos H, Bailey SM, Gussak LS, et al.  Relations of body habitus, fitness level, and cardiovascular risk factors including lipoproteins and apolipoproteins in a rural and urban Costa Rican population. Arterioscler Thromb. 1991;11:1077–1088
  15. Peeples LH, Carpenter JW, Israel RG, et al.  Alterations in low-density lipoproteins in subjects with abdominal adiposity. Metabolism. 1989;38:1029–1036
  16. Terry RB, Wood PD, Haskell WL, et al.  Regional adiposity patterns in relation to lipids, lipoprotein cholesterol, and lipoprotein subfraction mass in men. J Clin Endocrinol Metab. 1989;68:191–199
  17. Selby JV, Austin MA, Newman B, et al.  LDL subclass phenotypes and the insulin resistance syndrome in women. Circulation. 1993;88:381–387
  18. Houmard JA, Wheeler WS, McCammon MR, et al.  An evaluation of waist to hip ratio measurement methods in relation to lipid and carbohydrate metabolism in men. Int J Obes. 1991;15:181–188
  19. Brozek J, Keys A. The evaluation of leanness-fatness in man: Norms and interrelations. Br J Nutr. 1951;5:194–206
  20. Brozek J, Grande F, Anderson JT, et al.  Densitometric analysis of body composition: Revision of some quantitative assumptions. Ann NY Acad Sci. 1963;110:113–140
  21. Assmann G, Schulte H. Relation of high-density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience). Am J Cardiol. 1992;70:733–737
  22. Lee IM, Manson JE, Hennekens CH, et al.  Body weight and mortality. In: A 27-year follow-up of middle-aged men. ed 2. JAMA. 270:1993;p. 2823–2828
  23. Matthews DR, Hosker JP, Rudenski AS, et al.  Homeostasis model assessment: Insulin resistance and B-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–419
  24. Winocour PH, Kaluvya S, Ramaiya K, et al.  Relation between insulinemia, body mass index, and lipoprotein composition in healthy, nondiabetic men and women. Arterioscler Thromb. 1992;12:393–402
  25. Lindgren FT. Preparative ultracentrifugal laboratory procedures and suggestions for lipoprotein analysis. In:  Perkins EG editors. Analysis of Lipids and Lipoproteins. Champaign, IL: American Oil Chemists' Society; 1975;p. 204–224
  26. Baumstark MW, Kreutz W, Berg A, et al.  Structure of human low-density lipoprotein subfractions, determined by x-ray small-angle scattering. Biochim Biophys Acta. 1990;1037:48–57
  27. Knott TJ, Pease RJ, Powell LM, et al.  Complete protein sequence and identification of structural domains of human apolipoprotein B. Nature. 1986;323:734–738
  28. Yang CY, Chen SH, Gianturco SH, et al.  Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100. Nature. 1986;323:738–742
  29. Terry RB, Stefanick ML, Haskell WL, et al.  Contributions of regional adipose tissue depots to plasma lipoprotein concentrations in overweight men and women: Possible protective effects of thigh fat. Metabolism. 1991;40:733–740
  30. Coon PJ, Bleeker ER, Drinkwater DT, et al.  Effects of body composition and exercise capacity on glucose tolerance, insulin, and lipoprotein lipids in healthy older men: A cross-sectional and longitudinal intervention study. Metabolism. 1989;38:1201–1209
  31. Sosenko JM, Kato M, Soto R, et al.  The relation between the plasma lipoprotein pattern and the waist/hip ratio in non-diabetic individuals. J Clin Epidemiol. 1990;43:1149–1156
  32. Tatami R, Mabuchi H, Ueda K, et al.  Intermediate-density lipoprotein and cholesterol-rich very low density lipoprotein in angiographically determined coronary artery disease. Circulation. 1981;64:1174–1184
  33. Krauss RM, Williams PT, Brensike J, et al.  Intermediate-density lipoproteins and progression of coronary artery disease in hypercholesterolaemic men. Lancet. 1987;2:62–66
  34. Steiner G, Schwartz L, Shumak S, et al.  The association of increased levels of intermediate-density lipoproteins with smoking and with coronary artery disease. Circulation. 1987;75:124–130
  35. Bray GA. Complications of obesity. Ann Intern Med. 1985;103:1052–1062
  36. Després JP. Lipoprotein metabolism in visceral obesity. Int J Obes. 1991;15:45–52
  37. Krauss RM, Williams PT, Lindgren FT, et al.  Coordinate changes in levels of human serum low and high density lipoprotein subclasses in healthy men. Arteriosclerosis. 1988;8:155–162
  38. Kissebah AH, Alfarsi S, Adams PW. Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: Normolipemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia. Metabolism. 1981;30:856–868
  39. Kesaniemi YA, Grundy SM. Overproduction of low density lipoproteins associated with coronary heart disease. Arteriosclerosis. 1983;3:40–46
  40. Ginsberg HN, Le NA, Gibson JC. Regulation of the production and catabolism of plasma low density lipoproteins in hypertriglyceridemic subjects: Effects of weight loss. J Clin Invest. 1985;75:586–595
  41. Deckelbaum RJ, Granot E, Oschry Y, et al.  Plasma triglyceride determines structure-composition in low and high density lipoproteins. Arterioscler Thromb. 1984;4:225–231
  42. Halle M, Berg A, Baumstark MW. Differences in concentration and composition of LDL subfraction particles in hypercholesterolemic men with and without hypertriglyceridemia. Nutr Metab Cardiovasc Dis. 1993;3:179–184
  43. Berg A, Frey I, Baumstark MW, et al.  Physical activity and lipoprotein lipid disorders. Sports Med. 1994;17:6–21
  44. de Graaf J, Swinkels DW, de Haan A, et al.  Both inherited susceptibility and environmental exposure determine the low-density lipoprotein-subfraction pattern distribution in healthy Dutch families. Am J Hum Genet. 1992;51:1295–1310
  45. Auwerx JH, Marzetta CA, Hokanson JE, et al.  Large buoyant LDL-like particles in hepatic lipase deficiency. Arterioscler Thromb. 1989;9:319–325
  46. Karpe F, Tornvall P, Olivecrona T, et al.  Composition of human low density lipoprotein: Effects of postprandial triglyceride-rich lipoproteins, lipoprotein lipase, hepatic lipase and cholesteryl ester transfer protein. Atherosclerosis. 1993;98:33–49

PII: 0026-0495(95)90134-5

Metabolism - Clinical and Experimental
Volume 44, Issue 11 , Pages 1384-1390 , November 1995