Metabolism - Clinical and Experimental
Volume 44, Issue 6 , Pages 691-694 , June 1995

A tumor necrosis factor-β polymorphism associated with hypertriglyceridemia in non-insulin-dependent diabetes mellitus

Received 24 December 1993 ,Accepted 6 November 1994.

References 

  1. Renard E, Dupuy AM, Monnier L, et al.  DNA restriction polymorphisms of the apolipoprotein AI-CIII-AIV gene cluster: A genetic determinant of atherosclerosis in type 2 (non-insulin-dependent) diabetes mellitus. Diabetic Med. 1991;8:354–360
  2. Mandrup-Poulsen T, Owerbach D, Nerup J, et al.  Insulin-gene flanking region sequences, diabetes mellitus and atherosclerosis: A review. Diabetologia. 1985;28:556–564
  3. Adi S, Pllock AS, Shigenaga JK, et al.  Role for monokines in the metabolic effects of endotoxin. In: Interferon-gamma restores responsiveness of C3H/HeJ mice in vivo. ed 2. J Clin Invest. 89:1992;p. 1603–1609
  4. Feingold KR, Soued M, Adi S, et al.  Tumor necrosis factor-increased hepatic very-low-density lipoprotein production and increased serum triglyceride levels in diabetic rats. Diabetes. 1990;39:1569–1574
  5. Molving J, Pociot F, Baek L, et al.  Monocyte function in IDDM patients and healthy individuals. Scand J Immunol. 1990;32:297–311
  6. Muls E, Blaton V, Rosseneu M, et al.  Serum lipids and apolipoprotein A1, A2 and B in hyperthyroidism before and after treatment. J Clin Endocrinol Metab. 1982;55:459–464
  7. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning. In: ed 2. A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory; 1989;
  8. Southern EM. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975;98:503–517
  9. Pociot F, Molving J, Wogensen L, et al.  A tumor necrosis factor beta gene polymorphism in relation to monokine secretion and insulin-dependent diabetes mellitus. Scand J Immunol. 1991;33:37–49

 Supported by a grant from Planicid (SAL 90/0426), CICYT, Madrid, Spain.

PII: 0026-0495(95)90177-9

Metabolism - Clinical and Experimental
Volume 44, Issue 6 , Pages 691-694 , June 1995