Metabolism - Clinical and Experimental
Volume 44, Issue 6 , Pages 739-744 , June 1995

Increased transendothelial permeation of albumin by high glucose concentration

Received 12 April 1994 ,Accepted 12 August 1994.

References 

  1. Alpert JS, Coffman JD, Balodimos MC, et al.  Capillary permeability and blood flow in skeletal muscle of patients with diabetes mellitus and genetic prediabetes. N Engl J Med. 1972;286:454–460
  2. Parving HH, Noer I, Deckert T. The effect of metabolic regulation on microvascular permeability to small and large molecules in short-term juvenile diabetes. Diabetologia. 1978;12:161–166
  3. Bollinger A, Frey J, Jager K, et al.  Pattern of diffusion through skin capillaries in patients with long-term diabetes. N Engl J Med. 1982;307:1305–1310
  4. Chuha-Vaz JG, Gray JR, Zeimer RC, et al.  Characterization of the early stage of diabetic retinopathy by vitreous fluorophotometry. Diabetes. 1985;34:54–59
  5. Danowski TS, Fisher ER, Khurana RC, et al.  Muscle capillary basement membrane in juvenile diabetes mellitus. Metabolism. 1972;21:1125–1132
  6. Williamson JR, Kilo C. Basement membrane thickening and diabetic microangiopathy. Diabetes. 1976;25:925–927 suppl 2
  7. Raskin P, Petri AO, Unger R, et al.  The effect of diabetic control ont he width of skeletal-muscle capillary basement membrane in patients with type 1 diabetes mellitus. N Engl J Med. 1983;309:1546–1550
  8. Cahill GF, Etgimides DD, Freindel N. Control and diabetes. N Engl J Med. 1976;294:1004–1005
  9. Pirart J. Diabetes mellitus and its degenerative complications: A prospective study of 4,400 patients observed between 1947 and 1973. Diabetes Care. 1978;1:252–263
  10. Kilzer P, Chang K, Marvel J, et al.  Albumin permeation of new vessels is increased in diabetic rats. Diabetes. 1985;34:333–336
  11. Williamson JR, Chang K, Rowold E, et al.  Islets transplantation in diabetic Lewis rats prevent and reverse diabetic-induced increases in vascular permeability but do not reverse collagen solubility change. Diabetologia. 1986;29:392–396
  12. Chang K, Tomlinson M, Jeffery JR, et al.  Galactose ingestion increases vascular permeability and collagen solubility in normal male rats. J Clin Invest. 1987;79:367–373
  13. Lightman S, Rechthand E, Terubayashi H, et al.  Permeability changes in blood-retinal barrier of galactosemic rats are prevented by aldose reductase inhibitor. Diabetes. 1987;36:1271–1275
  14. Williamson JR, Ostrow E, Eades D, et al.  Glucose-induced microvascular functional changes in nondiabetic rats are stereo-specific and are prevented by an aldose reductase inhibitor. J Clin Invest. 1990;85:1167–1172
  15. Taylor RF, Price TH, Schwartz SM, et al.  Neutrophil-endothelial cell interactions on endothelial monolayers grown on micropore filters. J Clin Invest. 1981;67:584–587
  16. Hashida R, Anamizu C, Yagiu-Mizuno Y, et al.  Transcellular transport of fluorescein dextran through an arterial endothelial cell monolayer. Cell Struct Funct. 1986;11:343–349
  17. Inoguchi T, Umeda F, Ono H, et al.  Abnormality in prostacyclin-stimulatory activity in sera from diabetics. Metabolism. 1989;38:837–842
  18. Territo M, Berliner JA, Fogelman AM. Effect of monocyte migration on low density lipoprotein transport across aortic endothelial cell monolayers. J Clin Invest. 1984;74:2279–2284
  19. Stribling D, Mirrlees DJ, Harrison HE, et al.  Properties of ICI 128,436, a novel aldose reductase inhibitor, and its effect on diabetic complication in the rat. Metabolism. 1985;34:336–344
  20. Wroblewski F, LaDue JS. Lactic dehydrogenase activity in blood. In: ed 2. Proc Soc Exp Biol Med. 90:1955;p. 210–213
  21. Keller HU, Hess JW, Cottier H. The in vitro assessment of leukocyte chemotaxis. Antibiot Chemother. 1974;19:112–125
  22. Malone JI, Knox C, Benfords S, et al.  Red cell sorbitol: An indication of diabetic control. Diabetes. 1980;29:861–864
  23. Lowry DH, Rosebrough J, Farr AL, et al.  Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265–275
  24. Berliner JA. Formation of enlarged mitochondria in a liver cell line in response to a synthetic glucocorticoid. J Cell Biol. 1979;64:711–716
  25. Simionescu M, Simionescu N. Isolation of endothelial cells from the heart microvasculature. Microvasc Res. 1978;16:426–452
  26. Simionescu N. Cellular aspects of transcapillary exchange. Physiol Rev. 1983;63:1536–1579
  27. Simionescu N, Simionescu M, Palade GE. Open junctions in the endothelium of the post-capillary venules of the diaphragm. J Cell Biol. 1978;79:27–44
  28. Ghitescu L, Fixman A, Simionescu M, et al.  Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: Receptor-mediated transcytosis. J Cell Biol. 1986;102:1304–1311
  29. Milici AJ, Watrous NE, Stukenbrok H, et al.  Transcytosis of albumin in capillary endothelium. J Cell Biol. 1987;105:2603–2612
  30. Lorenzi M, Cagliero E, Toledo S. Glucose toxicity for human endothelial cells in culture. Diabetes. 1985;34:621–627
  31. Lorenzi M, Montisano DF, Toledo S, et al.  High glucose induces DNA damage in cultured human endothelial cells. J Clin Invest. 1986;77:322–325
  32. Winegard AI. Does a common mechanism induce the diverse complications of diabetes?. Diabetes. 1987;36:396–406
  33. Yorek MA. The effect of elevated glucose levels on myo-inositol metabolism in cultured bovine aortic endothelial cells. Metabolism. 1989;38:16–22
  34. Sussman I, Carson MP, Schultz V, et al.  Chronic exposure to high glucose decreases myo-inositol in cultured cerebral microvascular pericytes but not in endothelium. Diabetologia. 1988;31:771–775
  35. Bylander JE, Sense DA. Elicitation of sorbitol accumulation in cultured human proximal tubule cells by elevated glucose concentrations. Diabetes. 1990;39:949–952
  36. Haneda M, Kikkawa R, Arimura T, et al.  Glucose inhibits myo-inositol content in cultured rat glomerular mesangial cells. Metabolism. 1990;39:40–45
  37. Yamashita T, Umeda F, Hashimoto T, et al.  Effect of glucose on Na,K-ATPase activity in cultured bovine aortic endothelial cells. Endocrinol Jpn. 1992;39:1–7
  38. Wolf BA, Williamson JR, Eason RA, et al.  Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels. J Clin Invest. 1990;87:31–38
  39. Inoguchi T, Battan R, Handler E, et al.  Preferential elevation of protein kinase C isoform and diacylglycerol levels in the aorta and heart of diabetic rats. In: ed 2. Proc Natl Acad Sci USA. 89:1992;p. 11059–11063
  40. Lynch JJ, Ferro TJ, Bulumenstock FA, et al.  Increased endothelial albumin permeability mediated by protein kinase C activation. J Clin Invest. 1990;85:1991–1998
  41. Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes. 1991;40:405–412
  42. Shasby DM, Lind SE, Shasby SS, et al.  Reversible oxidant-induced increase in albumin transfer across cultured endothelium: Alterations in cell shape and calcification homeostasis. Blood. 1985;65:605–614
  43. Predescu D, Simionescu M, Simionescu N, et al.  Binding and transcytosis of glycoalbumin by the microvascular endothelium of the murine myocardium: Evidence that glycoalbumin behaves as a bifunctional ligand. J Cell Biol. 1988;107:1729–1738
  44. Espsito C, Gerlach H, Brett J, et al.  Endothelial receptor-mediated binding of glucose-modified albumin is associated with increase monolayer permeability and modulation of cell surface coagulant properties. J Exp Med. 1989;170:1387–1407

PII: 0026-0495(95)90186-8

Metabolism - Clinical and Experimental
Volume 44, Issue 6 , Pages 739-744 , June 1995

Article Tools