Metabolism - Clinical and Experimental
Volume 44 , Pages 18-23 , October 1995

Effect of insulin and insulin-like growth factor-1 on glucose transport and its transporters in soleus muscle of lean and obese mice

References 

  1. De Meyts P. The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling. Diabetologia. 1994;37(suppl 2):S135–S148
  2. Rechler MM, Nissley SP. The nature and regulation of the receptors for insulin-like growth factors. Annu Rev Physiol. 1985;47:425–442
  3. Froesch ER. Recombinant human insulin-like growth factor-I: A therapeutic challenge for diabetes mellitus. Diabetologia. 1994;37(suppl 2):S179–S185
  4. Schoenle EJ, Zenobi PD, Torresani T, et al.  Recombinant human insulin-like growth factor I (rhIGFI) reduces hyperglycaemia in patients with extreme insulin resistance. Diabetologia. 1991;34:675–679
  5. Le Marchand-Brustel Y, Jeanrenaud B, Freychet P. Insulin binding and effects in isolated soleus muscle of lean and obese mice. Am J Physiol. 1978;234:E348–E358
  6. Heydrick SJ, Jullien D, Gautier N, et al.  Defect in skeletal muscle phosphatidylinositol-3-kinase in obese insulin-resistant mice. J Clin Invest. 1993;91:1358–1366
  7. Poggi C, Le Marchand-Brustel Y, Zapf J, et al.  Effects and binding of insulin-like growth factor I in the isolated soleus muscle of lean and obese mice: Comparison with insulin. Endocrinology. 1979;105:723–730
  8. Lund S, Flyvbjerg A, Holman GD, et al.  Comparative effects of IGF-I and insulin on the glucose transporter system in rat muscle. Am J Physiol. 1994;267:E461–E466
  9. Van Obberghen E. Signalling through the insulin receptor and the insulin-like growth factor-I receptor. Diabetologia. 1994;37:S125–S134
  10. White MF, Kahn CR. The insulin signaling system. J Biol Chem. 1994;269:1–4
  11. Giorgetti S, Pelicci PG, Pelicci G, et al.  Involvement of src-homology/collagen (SHC) proteins in signaling through the insulin receptor and the insulin-like-growth-factor-I-receptor. Eur J Biochem. 1994;223:195–202
  12. Myers MG, Sun XJ, White MF. The IRS-1 signaling system. TIBS. 1994;19:289–293
  13. Sun XJ, Miralpeix M, Myers MG, et al.  Expression and function of IRS-1 in insulin signal transmission. J Biol Chem. 1992;267:22662–22672
  14. Tanti J-F, Grémeaux T, Van Obberghen E, et al.  Insulin receptor substrate 1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase. Biochem J. 1994;304:17–21
  15. Tanti J-F, Grémeaux T, Van Obberghen E, et al.  Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling. J Biol Chem. 1994;269:6051–6057
  16. Cheatham B, Vlahos CJ, Cheatham L, et al.  Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol. 1994;14:4902–4911
  17. Okada T, Kawano Y, Sakakibara T, et al.  Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. In: Studies with a selective inhibitor wortmannin. ed 2. J Biol Chem. 269:1994;p. 3568–3573
  18. Simpson IA, Cushman SW. Hormonal regulation of mammalian glucose transport. Annu Rev Biochem. 1986;55:1059–1089
  19. Yu KT, Czech M. The type I insulin-like growth factor receptor mediates the rapid effects of multiplication-stimulating activity on membrane transport systems in rat soleus muscle. J Biol Chem. 1984;259:3090–3095
  20. Le Marchand Y, Freychet P, Jeanrenaud B. Longitudinal study on the establishment of insulin resistance in hypothalamic obese mice. Endocrinology. 1978;102:74–85
  21. Le Marchand-Brustel Y, Grémeaux T, Ballotti R, et al.  Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice. Nature. 1985;315:676–679
  22. Le Marchand-Brustel Y, Freychet P. Studies of insulin insensitivity in soleus muscles of obese mice. Metabolism. 1978;27:1982–1993
  23. Cascieri MA, Slater EE, Vicario PP, et al.  Impaired insulinlike growth factor I-mediated stimulation of glucose incorporation into glycogen in vivo on the ob/ob mouse. Diabetologia. 1989;32:342–347
  24. Livingston N, Pollare T, Lithell H, et al.  Characterisation of insulin-like growth factor I receptor in skeletal muscles of normal and insulin resistant subjects. Diabetologia. 1988;31:871–877
  25. Jacob RJ, Sherwin RS, Greenawalt K, et al.  Simultaneous insulinlike growth factor I and insulin resistance in obese Zucker rats. Diabetes. 1992;41:691–697
  26. Dohm GD, Elton CW, Raju MS, et al.  IGF-I-stimulated glucose transport in human skeletal muscle and IGF-I resistance in obesity and NIDDM. Diabetes. 1990;39:1028–1032
  27. Wardzala LJ, Jeanrenaud B. Potential mechanism of insulin action on glucose transport in the isolated rat diaphragm. In: Apparent translocation of intracellular transport units to the plasma membrane-. ed 2. J Biol Chem. 256:1981;p. 7090–7093
  28. Le Marchand-Brustel Y, Olichon-Berthe C, Grémeaux T, et al.  Glucose transporter in insulin sensitive tissues of lean and obese mice. In: Effect of the thermogenic agent BRL 26830A. ed 2. Endocrinology. 127:1990;p. 2687–2695
  29. Koranyi L, James D, Mueckler M, et al.  Glucose transporter levels in spontaneously obese (db/db) insulin resistant mice. J Clin Invest. 1990;85:962–967
  30. Pedersen O, Bak JF, Andersen PH, et al.  Evidence against altered expression of GLUT1 or GLUT4 in skeletal muscle of patients with obesity or NIDDM. Diabetes. 1990;39:865–870
  31. Kahn BB, Pedersen O. Suppression of GLUT4 expression in skeletal muscle of rats that are obese from high fat feeding but not from high carbohydrate feeding or genetic obesity. Endocrinology. 1993;132:13–22
  32. Kahn BB. Facilitative glucose transporters: Regulatory mechanisms and dysregulation in diabetes. J Clin Invest. 1992;89:1367–1374
  33. Heydrick SJ, Gautier N, Olichon-Berthe C, et al.  Early alteration of insulin stimulation of PI 3-kinase in muscle and adipocyte from goldthioglucose obese mice. Am J Physiol. 1995;268:E604–E612
  34. Hiles ID, Otsu M, Volinia S, et al.  Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit. Cell. 1992;70:419–429
  35. Schu PV, Takegawa K, Fry MJ, et al.  Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science. 1993;260:88–91
  36. Giorgetti S, Ballotti R, Kowalski-Chauvel A, et al.  Insulin stimulates phosphatidylinositol-3-kinase activity in rat adipocytes. Eur J Biochem. 1992;207:599–606
  37. Kelly KL, Ruderman NB, Chen KS. Phosphatidylinositol-3-kinase in isolated rat adipocytes. J Biol Chem. 1992;267:3423–3428
  38. Hadari YR, Tzahar E, Nadiv O, et al.  Insulin and insulinomimetic agents induce activation of phosphatidylinositol 3′-kinase upon its association with pp185 (IRS-1) in intact rat livers. J Biol Chem. 1992;267:17483–17486

 Supported by grants from the Institut National de la Santé et de la Recherche Médicale (France) and the Université de Nice. S.J. Heydrick (Poste Vert) and D. Jullien (Poste Accueil) were supported by INSERM.

PII: 0026-0495(95)90216-3

Metabolism - Clinical and Experimental
Volume 44 , Pages 18-23 , October 1995