Metabolism - Clinical and Experimental
Volume 52, Issue 3 , Pages 328-332 , March 2003

Early vascular damage in primary hypoalphalipoproteinemia

Received 22 April 2002 ,Accepted 21 October 2002.

References 

  1. Funke H. Genetic determinants of high density lipoprotein levels. Curr Opin Lipidol. 1997;8:189–196
  2. Gordon T, Castelli WP, Hjortland MC, et al.  Diabetes, blood lipids, and the role of obesity in coronary heart disease risk for women. The Framingham study. Ann Intern Med. 1977;87:393–397
  3. Jacobs DR, Mebane IL, Bangdiwala SI, et al.  High density lipoprotein cholesterol as a predictor of cardiovascular disease in men and women: The follow up study of the Lipid Research Clinics Prevalence Study. Am J Epidemiol. 1990;131:32–47
  4. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001;285:2486–2497
  5. Rubins HB, Robins SJ, Collins D, et al. , for the Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group   Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. N Engl J Med. 1999;341:410–418
  6. Ballantyne CM, Herd JA, Ferlic LL, et al.  Influence of low HDL on progression of coronary artery disease and response to fluvastatin therapy. Circulation. 1999;99:736–743
  7. Corretti MC, Plotnick GD, Vogel RA. Technical aspects of evaluating brachial artery vasodilatation using high-frequency ultrasound. Am J Physiol. 1995;268:H1397–H1404
  8. Anderson TJ, Uehata A, Gerhard MD, et al.  Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol. 1995;26:1235–1241
  9. O'Leary DH, Polak JF, Kronmal RA, et al for the Cardiovascular Health Study Collaborative Research Group . Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. N Engl J Med. 1999;340:14–22
  10. Chambless LE, Heiss G, Folsom AR, et al.  Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: The Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993. Am J Epidemiol. 1997;146:483–494
  11. Menotti A, Seccareccia F, Lanti M. Mean levels and distribution of some cardiovascular risk factors in Italy in the 1970's and the 1980's. G Ital Cardiol. 1995;25:1539–1572
  12. Luscher TF. Vascular protection: Current possibilities and future perspectives. Int J Clin Pract. 2001;117(suppl):3–6
  13. Friedewald WT, Levy RI, Frederickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without the use of ultracentrifuge. Clin Chem. 1991;18:685–690
  14. Marchesi S, Lupattelli G, Schillaci G, et al.  Impaired flow-mediated vasoactivity during post-prandial phase in young healthy men. Atherosclerosis. 2000;153:397–402
  15. Corretti MC, Anderson TJ, Benjamin EJ, et al.  Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: A report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol. 2002;39:257–265
  16. Vaudo G, Schillaci G, Evangelista F, et al.  Arterial wall thickening at different sites and its association with left ventricular hypertrophy in newly diagnosed essential hypertension. Am J Hypertens. 2000;13:324–331
  17. Schillaci G, Vaudo G, Marchesi S, et al.  Optimizing assessment of carotid and femoral intima-media thickness in essential hypertension. Am J Hypertens. 2001;14:1025–1031
  18. Yuhanna IS, Zhu Y, Cox BE, et al.  High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase. Nat Med. 2001;7:853–857
  19. Vinals M, Martinez-Gonzalez J, Badimon L. Regulatory effects of HDL on smooth muscle cell prostacyclin release. Arterioscler Thromb Vasc Biol. 1999;19:2405–2411
  20. Oravec S, Demuth K, Myara I, et al.  The effect of high density lipoprotein subfractions on endothelial eicosanoid secretion. Thromb Res. 1998;92:65–71
  21. Matsuda Y, Hirata K, Inoue N, et al.  High density lipoprotein reverses inhibitory effect of oxidized low density lipoprotein on endothelium-dependent arterial relaxation. Circ Res. 1993;72:1103–1109
  22. Uittenbogaard A, Shaul PW, Yuhanna IS, et al.  High density lipoprotein prevents oxidized low density lipoprotein induced inhibition of endothelial nitric-oxide synthase localization and activation in caveolae. J Biol Chem. 2000;275:11278–11283
  23. Maier JA, Barcenghi L, Pagani F, et al.  The protective role of high density lipoprotein on oxidized low density lipoprotein induced U937/endothelial cell interactions. Eur J Biochem. 1994;221:35–41
  24. Salonen JT, Yla-Herttuala S, Yamamoto R, et al.  Autoantibody against oxidised LDL and progression of carotid atherosclerosis. Lancet. 1992;339:883–887
  25. Stafforini DM, Zimmermann GA, Mcintyre TM, et al.  The platelet activating factor acetylhydrolase from human plasma prevents oxidative modification of low density lipoproteins. Trans Am Assoc Physiol. 1993;106:44–63
  26. Mackness MI, Arrol S, Durrington PN. Paraoxonase prevents accumulation of lipoperoxides in low density lipoproteins. FEBS Lett. 1991;286:152–154
  27. Kelso GJ, Stuart WD, Richetr RJ, et al.  Apolipoprotein J is associated with paraoxonase in human plasma. Biochemistry. 1994;33:832–839
  28. Kuhn FE, Mohler ER, Satler LF, et al.  Effects of high density lipoprotein on acetylcholine-induced coronary vasoreactivity. Am J Cardiol. 1991;68:1425–1430
  29. Toikka JO, Ahotupa M, Viikari JS, et al.  Constantly low HDL-cholesterol concentration relates to endothelial dysfunction and increased in vivo LDL-oxidation in healthy young men. Atherosclerosis. 1999;147:133–138
  30. Sarabi M, Vessby B, Millgard J, et al.  Endothelium-dependent vasodilation is related to the fatty acid composition of serum lipids in healthy subjects. Atherosclerosis. 2001;156:349–355
  31. Spieker LE, Sudano I, Hurlimann D, et al.  High-density lipoprotein restores endothelial function in hypercholesterolemic men. Circulation. 2002;105:1399–1402
  32. Chambless LE, Folsom AR, Davis V, et al.  Risk factors for progression of common carotid atherosclerosis: The Atherosclerosis Risk in Communities Study, 1987-1998. Am J Epidemiol. 2002;155:38–47
  33. Wilt TJ, Rubins HB, Robins SJ, et al.  Carotid atherosclerosis in men with low levels of HDL cholesterol. Stroke. 1997;28:1919–1925
  34. Bokemark L, Wikstrand J, Attvall S, et al.  Insulin resistance and intima-media thickness in the carotid and femoral arteries of clinically healthy 58-year-old men. The Atherosclerosis and Insulin Resistance Study (AIR) J Intern Med. 2001;249:59–67
  35. Baldassarre D, Amato M, Pustina L, et al.  Increased carotid artery intima-media thickness in subjects with primary hypoalphalipoproteinemia. Arterioscler Thromb Vasc Biol. 2002;22:317–322
  36. Poli A, Tremoli E, Colombo A, et al.  Ultrasonographic measurement of the common carotid artery wall thickness in hypercholesterolemic patients. A new model for the quantitation and follow-up of preclinical atherosclerosis in living human subjects. Atherosclerosis. 1988;70:253–261
  37. Lundman P, Eriksson MJ, Stuhlinger M, et al.  Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine. J Am Coll Cardiol. 2001;38:111–116
  38. Hashimoto M, Akishita M, Eto M, et al.  The impairment of flow-mediated vasodilatation in obese men with visceral fat accumulation. Int J Obes Relat Metab Disord. 1998;22:477–484
  39. Karason K, Wikstrand J, Sjostrom L, et al.  Weight loss and progression of early atherosclerosis in the carotid artery: A four-year controlled study of obese subjects. Int J Obes Relat Metab Disord. 1999;23:948–956
  40. Lupattelli G, Lombardini R, Schillaci G, et al.  Flow-mediated vasoactivity and circulating adhesion molecules in hypertriglyceridemia: Association with small, dense LDL cholesterol particles. Am Heart J. 2000;140:521–526

☆ Supported in part by Grant No. 9806174392-007 from the Italian Ministry of Education, University and Research (MIUR), Rome, Italy.

☆☆ Address reprint requests to Gaetano Vaudo, MD, Internal Medicine, Angiology, and Atherosclerosis, University of Perugia, via Brunacci Brunamonti 51, 06122 Perugia, Italy.

PII: S0026-0495(02)05206-X

doi: 10.1053/meta.2003.50070

Metabolism - Clinical and Experimental
Volume 52, Issue 3 , Pages 328-332 , March 2003

Article Tools