« Previous
Next »
Metabolism - Clinical and Experimental
Volume 52, Issue 3
, Pages 264-272
, March 2003
Chronic effects of dehydroepiandrosterone on rat adipose tissue metabolism
References
- . Dehydroepiandrosterone: The “missing link” between hyperinsulinemia and atherosclerosis?. FASEB J. 1992;6:3073–3075
- . Is dehydroepiandrosterone an antiobesity agent?. FASEB J. 1993;7:414–419
-
.
Dehydroepiandrosterone and body fat.
Obes Res. 1995;3(suppl 4):613S–616S
- . The antiobesity effects of dehydroepiandrosterone in rats. Proc Soc Exp Biol Med. 1991;196:8–16
-
The antiobesity effect of dehydroepiandrosterone in castrated or noncastrated obese Zucker male rats.
Obes Res. 1995;3(suppl 5):639S–643S
-
DHEA treatment reduces fat accumulation and protects against insulin resistance in male rats.
J Gerontol Biol Sci. 1998;53:B19–B24
- Increased lipolysis to β-adrenergic stimulation after dehydroepiandrosterone treatment in rats. Am J Physiol. 1995;268:R1374–R1380
-
.
Effects of acute administration of dehydroepiandrosterone-sulfate on adipose tissue mass and cellularity in male rats.
Int J Obes Relat Metab Dis. 1997;21:147–154
-
.
Dehydroepiandrosterone-sulfate (DHEAS) reduces adipocyte hyperplasia associated with feeding rats a high fat diet.
Int J Obes Relat Metab Dis. 1997;21:1058–1064
-
.
Adipose tissue as a storage organ.
In:
Bray GA, Bouchard C, James WPT editor.
Handbook of Obesity. New York, NY: Dekker; 1998;p. 379–395
- . Adipocyte hormone-sensitive lipase: A major regulator of lipid metabolism. Proc Nutr Soc. 1996;55:93–109
- . Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res. 1993;34:1057–1091
-
Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP-phosphodiesterase in rat fat cells by phosphorylation.
Proc Natl Acad Sci USA. 1990;7:533–537
- . The effects of oral dehydroepiandrosterone on endocrine-metabolic parameters in postmenopausal women. J Clin Endocrinol Metab. 1990;71:696–704
- Effects of replacement dose of dehydroepiandrosterone in men and women with advancing age. J Clin Endocrinol Metab. 1994;78:1360–1367
-
Metabolic effects of 12-month percutaneous dehydroepiandrosterone replacement therapy in postmenopausal women.
J Endocrinol. 1996;150(suppl):S43–S50
- Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women. J Clin Endocrinol Metab. 1997;82:3498–3505
-
High bioavailability of dehydroepiandrosterone administered percutaneously in the rat.
J Endocrinol. 1996;150(suppl):S107–S118
- Predominant androgenic component in the stimulatory effect of dehydroepiandrosterone on bone mineral density in the rat. J Endocrinol. 1997;157:433–442
- Effects of CP-336,156, a new nonsteroidal estrogen agonist/antagonist, on bone, serum cholesterol, uterus, and body composition in rat models. Endocrinology. 1998;139:2068–2076
-
Quantitation of androgenic and estrogenic steroids in rat and monkey serum using gas chromatography and negative chemical ionization mass spectrometry.
In: Proceedings of the 48th ASMS Conference on Mass Spectrometry and Allied Topics, Long Beach, CA. 2000;
- Lipogenesis and lipoprotein lipase in human adipose tissue. Reproducibility of measurements and relationships with fat cell size. Can J Physiol Pharmacol. 1984;62:1448–1452
- . Phosphodiesterase activity of rat and human adipose tissue. J Lab Clin Med. 1972;79:598–610
- . Guanine nucleotides and adenosine “Ri”-site analogues stimulate the membrane-bound low Km cyclic AMP phosphodiesterase of rat adipocytes. FEBS Lett. 1984;173:385–388
- Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265–275
- Hormone-sensitive lipase from rat. Methods Enzymol. 1981;71:636–646
- Hormone-sensitive lipase: quantitation of enzyme activity and mRNA level in small biopsies of human adipose tissue. Clin Chim Acta. 1993;216:183–189
- Regional and gender variations in adipose tissue lipolysis in response to weight loss. J Lipid Res. 1999;40:1559–1571
-
Major lipolytic defects in white adipocytes from different depots of a new model of type II diabetes: The obese SHR/N-cp rat.
Obes Res. 1995;3:630s;
(abstr)
- Molecular mechanisms underlying regional variations of catecholamine-induced lipolysis in rat adipocytes. Am J Physiol. 1995;268:E1135–E1142
- . Direct assessment of beta-adrenergic receptors in intact rat adipocytes by binding of [3H]-CGP 12177. Evidence for agonist high affinity complex and for β1- and β2-receptor subtypes. Eur J Biochem. 1985;146:339–346
- Human fat cell beta-adrenergic receptors: beta-agonist dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta1-antagonists. J Lipid Res. 1988;29:587–601
- Characterization of β1- and β3-adrenoceptors in intact brown adipocytes. Br J Pharmacol. 1995;114:275–282
- . Sex steroid hormones and adipose tissue metabolism in ovariectomized rats. Acta Physiol Scand. 1987;129:471–477
- . Tissue- and gender-specific modulation of lipoprotein lipase in intact and gonadectomised rats treated with dl-fenfluramine. Int J Obes. 1994;18:405–411
- . Hormonal activation of the cGMP-inhibited low-Km cyclic AMP phosphodiesterase of rat adipocytes from different sites: Influence of ovariectomy. Biochim Biophys Acta. 1992;1136:99–104
-
Testosterone treatment of ovariectomized rats: Effects on lipolysis regulation in adipocytes.
Acta Endocrinol. 1990;123:61–66
- Comparison of the lipolytic effects of norepinephrine and BRL37344 in rat brown and white adipocytes. Obes Res. 1994;2:424–431
- Post receptors events involved in the up-regulation of beta-adrenergic receptor mediated lipolysis by testosterone in rat white adipocytes. Endocrinology. 1993;132:1651–1657
- . At the cutting edge. Intracrinology. Mol Cell Endocrinol. 1991;78:C113–C118
- Effects of dehydroepiandrosterone treatment in rats with diet-induced obesity. J Nutr. 1990;120:1103–1114
- . Glucose metabolism in isolated adipocytes from lean and obese Zucker rats following treatment with dehydroepiandrosterone. Metabolism. 1985;34:278–284
- . Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes/obesity mutants and in aged normal mice. Diabetes. 1984;33:26–32
- The effect of dehydroepiandrosterone combined with a low-fat diet in spontaneously obese dogs: A clinical trial. Obes Res. 1998;6:20–28
-
.
The insulin-resistance-dyslipidemic syndrome of visceral obesity: Effect on patients' risk.
Obes Res. 1998;6(suppl 1):8S–18S
☆ Supported by the Natural Sciences and Engineering Research Council of Canada and EndoRecherche.
☆☆ Address reprint requests to Pascale Mauriège, PhD, Division of Kinesiology, Department of Social and Preventive Medicine, P.E.P.S., Laval University, Ste-Foy, Québec, Canada G1K 7P4.
PII: S0026-0495(02)05259-9
doi: 10.1053/meta.2003.50043
« Previous
Next »
Metabolism - Clinical and Experimental
Volume 52, Issue 3
, Pages 264-272
, March 2003
