Metabolism - Clinical and Experimental
Volume 55, Issue 3 , Pages 339-344 , March 2006

Maternal body size and birth weight: can insulin or adipokines do better?

  • Johan Verhaeghe

      Affiliations

    • Department of Obstetrics and Gynecology, Katholieke Universiteit Leuven, 3000 Leuven, Belgium
    • Corresponding Author InformationCorresponding author. Tel.: +32 16344212; fax: +32 16344205.
  • ,
  • Rita van Bree

      Affiliations

    • Department of Obstetrics and Gynecology, Katholieke Universiteit Leuven, 3000 Leuven, Belgium
  • ,
  • Erik Van Herck

      Affiliations

    • Laboratorium voor Experimentele Geneeskunde en Endocrinologie, Katholieke Universiteit Leuven, 3000 Leuven, Belgium

Received 16 March 2005 ,Accepted 9 September 2005.

References 

  1. Garn SM, Pesick SD. Relationship between various maternal body mass measures and size of the newborn. Am J Clin Nutr. 1982;36:664–668
  2. Abrams B, Altman SL, Pickett KE. Pregnancy weight gain: still controversial. Am J Clin Nutr. 2000;71(Suppl):1233S–1241S
  3. Institute of Medicine . Nutrition during pregnancy. Part I, weight gain. Washington (DC): National Academy Press; 1990;
  4. Niswender KD, Baskin DG, Schwartz MW. Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis. Trends Endocrinol Metab. 2004;15:362–369
  5. Verhaeghe J, van Bree R, Lambin S, et al. Adipokine profile and C-reactive protein in pregnancy: effects of glucose challenge response versus body mass index. J Soc Gynecol Investig. 2005;12:330–334
  6. Chan JL, Blüher S, Yiannakouris N, et al. Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: observational and interventional studies in humans. Diabetes. 2002;51:2105–2112
  7. Catalano PM, Tyzbir ED, Roman NM, et al. Longitudinal changes in insulin release and insulin resistance in non-obese pregnant women. Am J Obstet Gynecol. 1991;165:1667–1672
  8. Sattar N, Greer IA, Pirwani I, et al. Leptin levels in pregnancy: marker for fat accumulation and mobilization?. Acta Obstet Gynecol Scand. 1998;77:278–283
  9. Lewandowski K, Horn R, O'Callaghan CJ, et al. Free leptin, bound leptin, and soluble leptin receptor in normal and diabetic pregnancies. J Clin Endocrinol Metab. 1999;84:300–306
  10. Chandran M, Phillips SA, Ciaraldi T, et al. Adiponectin: more than just another fat cell hormone?. Diabetes Care. 2003;26:2442–2450
  11. Kirwan JP, Hauguel-De Mouzon S, Lepercq J, et al. TNF-α is a predictor of insulin resistance in human pregnancy. Diabetes. 2002;51:2207–2213
  12. Breschi MC, Seghieri G, Bartolomei G, et al. Relation of birth weight to maternal plasma glucose and insulin concentration during normal pregnancy. Diabetologia. 1993;36:1315–1321
  13. Catalano PM, Drago NM, Amini SB. Maternal carbohydrate metabolism and its relationship to fetal growth and body composition. Am J Obstet Gynecol. 1995;172:1464–1470
  14. Scholl TO, Stein TP, Smith WK. Leptin and maternal growth during adolescent pregnancy. Am J Clin Nutr. 2000;72:1542–1547
  15. Verhaeghe J, Pintiaux A, Van Herck E, et al. Placental GH, IGF-I, IGF-binding protein–1, and leptin during a glucose challenge test in pregnant women: relation with maternal body weight, glucose tolerance, and birth weight. J Clin Endocrinol Metab. 2002;87:2875–2882
  16. American Diabetes Association . Gestational diabetes mellitus. Diabetes Care. 2004;27(Suppl 1):S88–S90
  17. Verhaeghe J. Gestational diabetes mellitus: pathophysiology, screening and diagnosis, and management. In:  Van Assche FA editors. Diabetes and pregnancy. European practice in gynaecology and obstetrics. vol. 7:Amsterdam, The Netherlands: Elsevier B.V.; 2004;p. 15–27
  18. Davey DA, McGillivray I. The classification and definition of the hypertensive disorders of pregnancy. Am J Obstet Gynecol. 1988;158:892–898
  19. Devlieger H, Martens G, Bekaert A, et al. Standaarden van geboortegewicht-voor-zwangerschapsduur voor de Vlaamse boreling. Tijdschr Geneeskd. 2000;56:1–14[in Dutch]
  20. Jensen DM, Ovesen P, Beck-Nielsen H, et al. Gestational weight gain and pregnancy outcomes in 481 obese glucose-tolerant women. Diabetes Care. 2005;28:2118–2122
  21. Brown JE, Murtaugh MA, Jacobs DR, et al. Variation in newborn size according to pregnancy weight change by trimester. Am J Clin Nutr. 2002;76:205–209
  22. Anim-Nyame N, Sooranna SR, Steer PJ, et al. Longitudinal analysis of maternal plasma leptin concentrations during normal pregnancy and pre-eclampsia. Hum Reprod. 2000;15:2033–2036
  23. Reimer T, Koczan D, Gerber B, et al. Microarray analysis of differentially expressed genes in placental tissue of pre-eclampsia: up-regulation of obesity-related genes. Mol Hum Reprod. 2002;8:674–680
  24. Sandhofer A, Laimer M, Ebenbichler CF, et al. Soluble leptin receptor and soluble receptor-bound fraction of leptin in the metabolic syndrome. Obes Res. 2003;11:760–768
  25. Saldana TM, Siega-Riz AM, Adair LS, et al. The association between impaired glucose tolerance and birth weight among black and white women in central North Carolina. Diabetes Care. 2003;26:656–661
  26. Sermer M, Naylor CD, Gare DJ, et al. Impact of increasing carbohydrate intolerance on maternal-fetal outcomes in 3637 women without gestational diabetes: the Toronto Tri-Hospital Gestational Diabetes Project. Am J Obstet Gynecol. 1995;173:146–156
  27. Snyder J, Gray-Donald K, Koski KG. Predictors of infant birth weight in gestational diabetes. Am J Clin Nutr. 1994;59:1409–1414
  28. Cammu H, Martens G, De Coen K, et al. Perinatale activiteiten in Vlaanderen 2003. Brussel: vzw Studiecentrum voor Perinatale Epidemiologie; 2004;[in Dutch]
  29. Bhatia S, Faessen GH, Carland G, et al. A longitudinal analysis of maternal serum insulin-like growth factor I (IGF-I) and total and nonphosphorylated IGF-binding protein–1 in human pregnancies complicated by intrauterine growth restriction. J Clin Endocrinol Metab. 2002;87:1864–1870
  30. Chellakooty M, Vangsgaard K, Larsen T, et al. A longitudinal study of intrauterine growth and the placental growth hormone (GH)–insulin-like growth factor I axis in maternal circulation: associations between placental GH and fetal growth. J Clin Endocrinol Metab. 2004;89:384–391
  31. Gibson HM. Plasma volume and glomerular filtration rate in pregnancy and their relation to differences in fetal growth. J Obstet Gynaecol Br Commonw. 1973;80:1067–1074

PII: S0026-0495(05)00364-1

doi: 10.1016/j.metabol.2005.09.007

Metabolism - Clinical and Experimental
Volume 55, Issue 3 , Pages 339-344 , March 2006