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Volume 55, Issue 12, Pages 1561-1563 (December 2006)


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Higher levels of adiponectin in American than in Japanese men despite obesity

Takashi KadowakiabCorresponding Author Informationemail address, Akira Sekikawab, Tomonori Okamuraa, Tomoko Takamiyab, Atsunori Kashiwagic, Wahid R. Zakyb, Hiroshi Maegawac, Aiman El-Saedb, Yasuyuki Nakamurad, Rhobert W. Evansb, Daniel Edmundowicze, Yoshikuni Kitaa, Lewis H. Kullerb, Hirotsugu Ueshimaa

Received 3 March 2006; accepted 29 August 2006.

Abstract 

Levels of adiponectin are inversely associated with obesity levels. We examined the levels of adiponectin in American (n = 98) and Japanese (n = 92) men aged 40 to 49 years. Contrary to our expectations, the American men had higher levels of adiponectin than the Japanese men (13.3 ± 5.8 vs 7.3 ± 4.2 (μg/mL) despite higher levels of obesity. Smaller areas of visceral adipose tissue in American than in Japanese men may have resulted in the higher levels of adiponectin.

a Department of Health Science, Shiga University of Medical Science, Shiga 520-2192, Japan

b Graduate School of Public Health, University of Pittsburgh, PA 15213, USA

c Department of Medicine, Shiga University of Medical Science, Shiga 520-2192, Japan

d Department of Living and Welfare, Kyoto Women's University, Kyoto 605-8501, Japan

e University of Pittsburgh Medical Center, PA 15213, USA

Corresponding Author InformationCorresponding author. Department of Health Science, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan. Tel.: +81 77 548 2191; fax: +81 77 543 9732.

PII: S0026-0495(06)00300-3

doi:10.1016/j.metabol.2006.08.004


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