Metabolism - Clinical and Experimental
Volume 55, Issue 12 , Pages 1561-1563 , December 2006

Higher levels of adiponectin in American than in Japanese men despite obesity

  • Takashi Kadowaki

      Affiliations

    • Department of Health Science, Shiga University of Medical Science, Shiga 520-2192, Japan
    • Graduate School of Public Health, University of Pittsburgh, PA 15213, USA
    • Corresponding Author InformationCorresponding author. Department of Health Science, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan. Tel.: +81 77 548 2191; fax: +81 77 543 9732.
    • ,
  • Akira Sekikawa

      Affiliations

    • Graduate School of Public Health, University of Pittsburgh, PA 15213, USA
    • ,
  • Tomonori Okamura

      Affiliations

    • Department of Health Science, Shiga University of Medical Science, Shiga 520-2192, Japan
    • ,
  • Tomoko Takamiya

      Affiliations

    • Graduate School of Public Health, University of Pittsburgh, PA 15213, USA
    • ,
  • Atsunori Kashiwagi

      Affiliations

    • Department of Medicine, Shiga University of Medical Science, Shiga 520-2192, Japan
    • ,
  • Wahid R. Zaky

      Affiliations

    • Graduate School of Public Health, University of Pittsburgh, PA 15213, USA
    • ,
  • Hiroshi Maegawa

      Affiliations

    • Department of Medicine, Shiga University of Medical Science, Shiga 520-2192, Japan
    • ,
  • Aiman El-Saed

      Affiliations

    • Graduate School of Public Health, University of Pittsburgh, PA 15213, USA
    • ,
  • Yasuyuki Nakamura

      Affiliations

    • Department of Living and Welfare, Kyoto Women's University, Kyoto 605-8501, Japan
    • ,
  • Rhobert W. Evans

      Affiliations

    • Graduate School of Public Health, University of Pittsburgh, PA 15213, USA
    • ,
  • Daniel Edmundowicz

      Affiliations

    • University of Pittsburgh Medical Center, PA 15213, USA
    • ,
  • Yoshikuni Kita

      Affiliations

    • Department of Health Science, Shiga University of Medical Science, Shiga 520-2192, Japan
    • ,
  • Lewis H. Kuller

      Affiliations

    • Graduate School of Public Health, University of Pittsburgh, PA 15213, USA
    • ,
  • Hirotsugu Ueshima

      Affiliations

    • Department of Health Science, Shiga University of Medical Science, Shiga 520-2192, Japan

Received 3 March 2006 ,Accepted 29 August 2006.

References 

  1. Matsuzawa Y, Funahashi T, Nakamura T. Molecular mechanism of metabolic syndrome X contribution of adipocytokines adipocyte-derived bioactive substances. Ann N Y Acad Sci. 1999;892:146–154
  2. Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun. 1999;257:79–83
  3. Sekikawa A, Ueshima H, Zaky WR, et al. Much lower prevalence of coronary calcium detected by electron-beam computed tomography among men aged 40-49 in Japan than in the US, despite a less favorable profile of major risk factors. Int J Epidemiol. 2005;34:173–179
  4. Park KG, Park KS, Kim MJ, et al. Relationship between serum adiponectin and leptin concentrations and body fat distribution. Diabetes Res Clin Pract. 2004;63:135–142
  5. Kadowaki T, Sekikawa A, Murata K, et al. Japanese men have larger areas of visceral adipose tissue than Caucasian men in the same levels of waist circumference in a population-based study. Int J Obes (Lond). 2006;30:1163–1165
  6. Zhou BF, Stamler J, Dennis B, et al. Nutrient intakes of middle-aged men and women in China, Japan, United Kingdom, and United States in the late 1990s: the INTERMAP study. J Hum Hypertens. 2003;17:623–630

PII: S0026-0495(06)00300-3

doi: 10.1016/j.metabol.2006.08.004

Metabolism - Clinical and Experimental
Volume 55, Issue 12 , Pages 1561-1563 , December 2006

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