Metabolism - Clinical and Experimental
Volume 58, Issue 9 , Pages 1356-1365, September 2009

Glucose metabolism in children: influence of age, fasting, and infectious diseases

  • Wilco C.W.R. Zijlmans

      Affiliations

    • Department of Pediatrics, Diakonessen Hospital, PO Box 1814, Paramaribo, Suriname (SA)
    • Corresponding Author InformationCorresponding author. Tel.: +5978600200; fax: +597499224.
    • ,
  • Anne A.M.W. van Kempen

      Affiliations

    • Department of Pediatrics, Onze Lieve Vrouwe Gasthuis, Amsterdam 1091 BC, The Netherlands
    • ,
  • Mireille J. Serlie

      Affiliations

    • Metabolism Unit, Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam 1105 AZ, The Netherlands
    • ,
  • Hans P. Sauerwein

      Affiliations

    • Metabolism Unit, Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam 1105 AZ, The Netherlands

Received 8 February 2009; accepted 28 April 2009. published online 08 June 2009.

Abstract 

This review describes the occurrence of hypoglycemia in young children as a common and serious complication that needs to be avoided because of the high risk of brain damage and mortality. Young age, fasting, and severe infectious disease are considered important risk factors. The limited data on the effect of these risk factors on glucose metabolism in children are discussed and compared with data on glucose metabolism in adults. The observations discussed may have implications for further research on glucose kinetics in young children with infectious disease.

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PII: S0026-0495(09)00161-9

doi:10.1016/j.metabol.2009.04.020

Metabolism - Clinical and Experimental
Volume 58, Issue 9 , Pages 1356-1365, September 2009

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