Metabolism - Clinical and Experimental
Volume 59, Issue 4 , Pages 587-598, April 2010

Dysregulation of sterol regulatory element binding protein–1c in livers of morbidly obese women is associated with altered suppressor of cytokine signaling–3 and signal transducer and activator of transcription–1 signaling

  • Marshall B. Elam

      Affiliations

    • Department of Medicine and Research Service, Department of Veterans Affairs Medical Center, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    • Corresponding Author InformationCorresponding author. Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA. Tel.: +1 901 448 6000; fax: +1 901 448 7206.
    • Contributed equally to this study.
  • ,
  • Chandrahasa Yellaturu

      Affiliations

    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    • Contributed equally to this study.
  • ,
  • George E. Howell

      Affiliations

    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • Xiong Deng

      Affiliations

    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • George S. Cowan

      Affiliations

    • Department of Surgery, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • Poonam Kumar

      Affiliations

    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • Edwards A. Park

      Affiliations

    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • M. Lloyd Hiler

      Affiliations

    • Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • Henry G. Wilcox

      Affiliations

    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • Thomas A. Hughes

      Affiliations

    • Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • George A. Cook

      Affiliations

    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
  • ,
  • Rajendra Raghow

      Affiliations

    • Department of Medicine and Research Service, Department of Veterans Affairs Medical Center, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    • Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA

Received 1 May 2009; accepted 2 September 2009. published online 16 November 2009.

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 Disclosure statement: The authors have no conflicts of interest to disclose.

 Institutional approval: This study was approved by the Institutional Review Boards of the University of Tennessee Health Sciences Center and Baptist Memorial Hospital-Memphis.

PII: S0026-0495(09)00369-2

doi:10.1016/j.metabol.2009.09.001

Metabolism - Clinical and Experimental
Volume 59, Issue 4 , Pages 587-598, April 2010