Metabolism - Clinical and Experimental
Volume 59, Issue 7 , Pages 967-976, July 2010

α-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate–activated protein kinase–peroxisome proliferator-activated receptor-γ coactivator-1α signaling in the skeletal muscle of aged mice

  • Yi Wang

      Affiliations

    • State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100083, China
    • USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
  • ,
  • Xiaojie Li

      Affiliations

    • State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100083, China
    • USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
  • ,
  • Yuming Guo

      Affiliations

    • State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100083, China
  • ,
  • Lawrence Chan

      Affiliations

    • Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
  • ,
  • Xinfu Guan

      Affiliations

    • USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    • Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    • Corresponding Author InformationCorresponding author. USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA. Tel.: +1 713 798 9322; fax: +1 713 798 7100.

Received 28 May 2009; accepted 21 October 2009. published online 16 December 2009.

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 The work was done at the USDA/ARS Children's Nutrition Research Center.

 Conflicts of interest: The authors declare that there are no conflicts of interest associated with this manuscript.

PII: S0026-0495(09)00449-1

doi:10.1016/j.metabol.2009.10.018

Metabolism - Clinical and Experimental
Volume 59, Issue 7 , Pages 967-976, July 2010