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Metabolism - Clinical and Experimental
Volume 45, Supplement 1, Pages 1-131 (August 1996)
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New insights into the regulation of somatotrope function using genetic and transgenic models
L.A. Frohman
pages 1-3
Abstract | Abstract + References | Full-Text PDF (257 KB)


Regulation of somatostatin gene transcription by cyclic adenosine monophosphate
M. Montminy, P. Brindle, J. Arias, K. Ferreri, R. Armstrong
pages 4-7
Abstract | Abstract + References | Full-Text PDF (1632 KB)


Somatostatin receptor subtypes: Specific expression and signaling properties
A. Schonbrunn, Y.-Z. Gu, P. Dournard, A. Beaudet, G.S. Tannenbaum, P.J. Brown
pages 8-11
Abstract | Abstract + References | Full-Text PDF (407 KB)


Molecular and functional properties of somatostatin receptor subtypes
George Liapakis, Melanie Tallent, Terry Reisine
pages 12-13
Abstract | Abstract + References | Full-Text PDF (223 KB)


Molecular mechanisms of antiproliferative effect of somatostatin: Involvement of a tyrosine phosphatase
F. Lopez, J.P. Estève, L. Buscail, N. Delesque, N. Saint-Laurent, N. Vaysse, C. Susini
pages 14-16
Abstract | Abstract + References | Full-Text PDF (258 KB)


Binding properties of somatostatin receptor subtypes
Christian Bruns, Friedrich Raulf, Daniel Hoyer, Jürgen Schloos, Hermann Lübbert, Gisbert Weckbecker
pages 17-20
Abstract | Abstract + References | Full-Text PDF (455 KB)


Receptor-specific somatostatin analogs: Correlations with biological activity
David H. Coy, John E. Taylor
pages 21-23
Abstract | Abstract + References | Full-Text PDF (224 KB)


Improved analogs and novel delivery systems for somatostatin octapeptides
J.-P. Moreau, S. Kim, J.Z. Dong, F. Ignatious, S. Jackson, S.C. Moreau, B.A. Morgan, F. Touraud, J.E. Taylor, B. Tissier, M. Pellet, T. Davis
pages 24-26
Abstract | Abstract + References | Full-Text PDF (265 KB)


Sandostatin® LAR® (microencapsulated octreotide acetate) in acromegaly: Pharmacokinetic and pharmacodynamic relationships
Peter Grass, Peter Marbach, Christian Bruns, Ioana Lancranjan
pages 27-30
Abstract | Abstract + References | Full-Text PDF (310 KB)


Molecular biology of somatostatin receptor subtypes
Yogesh C. Patel, Michael Greenwood, Rosemarie Panetta, Nedim Hukovic, Stellios Grigorakis, Lauri-Ann Robertson, Coimbatore B. Srikant
pages 31-38
Abstract | Abstract + References | Full-Text PDF (1278 KB)


Somatostatin receptors and their subtypes in human tumors and in peritumoral vessels
Jean Claude Reubi, Jean-Claude Schaer, Jean A. Laissue, Beatrice Waser
pages 39-41
Abstract | Abstract + References | Full-Text PDF (268 KB)


Effector coupling of somatostatin receptor subtypes on human endocrine tumors
Akira Kubota, Yuichiro Yamada, Shinji Kagimoto, Susumu Seino, Yutaka Seino
pages 42-45
Abstract | Abstract + References | Full-Text PDF (388 KB)


Cellular abnormalities in pituitary tumors
Anna Spada, Andrea Lania, Simona Mantovani
pages 46-48
Abstract | Abstract + References | Full-Text PDF (301 KB)


The effects of the somatostatin analog octreotide on angiogenesis in vitro
Romano Danesi, Mario Del Tacca
pages 49-50
Abstract | Abstract + References | Full-Text PDF (208 KB)


Acromegaly
Shlomo Melmed
pages 51-52
Abstract | Abstract + References | Full-Text PDF (153 KB)


Relationships between pathological diagnosis and clinical parameters in acromegaly
J. Trouillas, G. Sassolas, M.-P. Guigard, P. Fonlupt, L. Ansaneli-Naves, G. Perrin
pages 53-56
Abstract | Abstract + References | Full-Text PDF (367 KB)


Cardiovascular aspects in acromegaly: Effects of treatment
Gaetano Lombardi, Annamaria Colao, Diego Ferone, Paolo Marzullo, Maria Luisa Landi, Salvatore Longobardi, Emilia Iervolino, Alberto Cuocolo, Serafino Fazio, Bartolomeo Merola, Luigi Sacca
pages 57-60
Abstract | Abstract + References | Full-Text PDF (290 KB)


Metabolic aspects of acromegaly and its treatment
H.-J. Quabbe, U. Plöckinger
pages 61-62
Abstract | Abstract + References | Full-Text PDF (206 KB)


Treatment options for acromegaly
M.C. Sheppard, P.M. Stewart
pages 63-64
Abstract | Abstract + References | Full-Text PDF (251 KB)


Acromegaly—the place of the neurosurgeon
R. Fahlbusch, J. Honegger, M. Buchfelder
pages 65-66
Abstract | Abstract + References | Full-Text PDF (157 KB)


Sandostatin® LAR®: A promising therapeutic tool in the management of acromegalic patients
I. Lancranjan, C. Bruns, P. Grass, P. Jaquet, J. Jervell, P. Kendall-Taylor, S.W.J. Lamberts, P. Marbach, H. Ørskov, G. Pagani, M. Sheppard, L. Simionescu
pages 67-71
Abstract | Abstract + References | Full-Text PDF (437 KB)


Presurgical octreotide: Treatment in acromegaly
Achille Stevenaert, Albert Beckers
pages 72-74
Abstract | Abstract + References | Full-Text PDF (241 KB)


Thyrotropin-secreting pituitary adenomas
P. Beck-Peccoz, L. Persani, S. Mantovani, D. Cortelazzi, C. Asteria
pages 75-78
Abstract | Abstract + References | Full-Text PDF (478 KB)


Nonfunctioning adenomas of the pituitary
Antonio Liuzzi, Vittorio Tassi, Maria Teresa Pirro, Matteo Zingrillo, Maria Rosaria Ghiggi, Iacopo Chiodini, Giuseppe Oppizzi, Massimo Barberis
pages 80-82
Abstract | Abstract + References | Full-Text PDF (294 KB)


Is there a role for somatostatin and its analogs in Cushing's syndrome?
W.W. de Herder, S.W.J. Lamberts
pages 83-85
Abstract | Abstract + References | Full-Text PDF (244 KB)


Somatostatin receptor expression in clinical immunology
P.M. van Hagen
pages 86-87
Abstract | Abstract + References | Full-Text PDF (169 KB)


Granulomas in murine schistosomiasis mansoni have a somatostatin immunoregulatory circuit
D.E. Elliott, J.V. Weinstock
pages 88-90
Abstract | Abstract + References | Full-Text PDF (363 KB)


Somatostatin, growth hormone, insulin-like growth factor-1, and diabetes: Friends or foes?
H. Ørskov
pages 91-95
Abstract | Abstract + References | Full-Text PDF (502 KB)


The relevance of somatostatin receptor expression in malignant lymphomas
P.J. van den Anker-Lugtenburg, B. Löwenberg, S.W.J. Lamberts, E.P. Krenning
pages 96-97
Abstract | Abstract + References | Full-Text PDF (937 KB)


Somatostatin and cancer
R.J. Robbins
pages 98-100
Abstract | Abstract + References | Full-Text PDF (329 KB)


Blockade of growth factor synthesis and growth factor action: Two possible sites of interference in allograft vessel disease and coronary bypass or balloon injury
P. Häyry, E. Aavik, M. Myllärniemi
pages 101-103
Abstract | Abstract + References | Full-Text PDF (281 KB)

Plenary lecture


Somatostatin analogs: Future directions
S.W.J. Lamberts, A.J. van der Lely, W.W. de Herder, L.J. Hofland
pages 104-106
Full-Text PDF (275 KB)


Long-term effects of radiotherapy for acromegaly
J.A.H. Wass
pages 107-108
Abstract | Abstract + References | Full-Text PDF (182 KB)


The role of somatostatin agonistic analogs in the treatment of acromegaly
George Tolis
pages 109-110
Abstract | Abstract + References | Full-Text PDF (219 KB)


Stereotactic radiosurgery of pituitary adenomas
E.D.F. Motti, M. Losa, S. Pieralli, A. Zecchinelli, B. Longobardi, E. Giugni, L. Ventrella
pages 111-114
Abstract | Abstract + References | Full-Text PDF (2573 KB)


Surgical therapy of pituitary adenomas
Massimo Giovanelli, Marco Losa, Pietro Mortini
pages 115-116
Abstract | Abstract + References | Full-Text PDF (230 KB)


Gs protein mutations and pituitary tumors: Functional correlates and possible therapeutic implications
G. Faglia, M. Arosio, A. Spada
pages 117-119
Abstract | Abstract + References | Full-Text PDF (300 KB)


Gs protein mutations and the pathogenesis and function of pituitary tumors
P.E. Harris
pages 120-122
Abstract | Abstract + References | Full-Text PDF (302 KB)


Role of the new growth hormone-releasing secretagogues in the diagnosis of some hypothalamopituitary pathologies
Felipe F. Casanueva, Dragan Micic, Manuel Pombo, Alfonso Leal, Lazaro Bokser, Jose L. Zugaza, Carlos Dieguez
pages 123-126
Abstract | Abstract + References | Full-Text PDF (368 KB)


Observations on the stimulation of growth hormone secretion in patients with growth hormone deficiency
P. Kendall-Taylor, A. Paxton, N.P. Koppiker
pages 127-128
Abstract | Abstract + References | Full-Text PDF (221 KB)


Somatostatin analogs in ectopic corticotropin production
K. von Werder, O.A. Muller, G.K. Stalla
pages 129-131
Abstract | Abstract + References | Full-Text PDF (269 KB)

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