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Masthead
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IFC
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Foreword
This supplement constitutes the sixth Annals of the Collège International de Recherche Servier (CIRS) and arises out of a 4-day symposium on Pain organized by CIRS in Quebec City, Canada, in September...
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Madeleine Tremblay-Servier
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S1
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New therapeutics for pain—an overview
The International Association for the Study of Pain defines pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such dam...
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Madhu Kalia,
Theodore B. VanItallie
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S2-S4
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Genetics of pain, opioids, and opioid responsiveness
Abstract: Pain is an integral part of the defense mechanisms required for survival. Several hereditary syndromes of complete or almost complete insensitivity to pain have been identified and include c...
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Johanne Tremblay,
Pavel Hamet
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S5-S8
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The role of corticosteroids and stress in chronic pain conditions
Abstract: The relationship between corticosteroids (endogenous and exogenous) and stress is well known, as is the use of steroids as concomitant treatment in pain management during acute inflammation....
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Bruce S. McEwen,
Madhu Kalia
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S9-S15
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Pain: sex differences and implications for treatment
Abstract: Women have a higher prevalence than men of several clinical pain conditions and of inflammation-mediated disorders. There is also increasing evidence for sex differences in sensitivity to ex...
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JoAnn E. Manson
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S16-S20
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Spinal glia and chronic pain
Abstract: Therapeutic management of chronic pain has not been widely successful owing to a lack of understanding of factors that initiate and maintain the chronic pain condition. Efforts to delineate ...
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James P. O'Callaghan,
Diane B. Miller
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S21-S26
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Neurosurgical treatments of intractable pain
Abstract: Intractable pain may require neurosurgical intervention. This review provides a critical update of neurosurgical techniques available to treat this condition. Neurosurgery can affect pain's ...
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Stylianos Nicolaidis
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S27-S31
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Gout: epitome of painful arthritis
Abstract: Arthritic pain and disability are at or near the top of the list of reasons adult patients seek medical attention. At least 47.8 million US residents have arthritis. In Europe, the magnitude...
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Theodore B. VanItallie
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S32-S36
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Fibromyalgia and the complex regional pain syndrome: similarities in pathophysiology and treatment
Abstract: Although the pain of fibromyalgia usually is not preceded by an injury to the involved tissue, whereas that of the complex regional pain syndrome usually starts at a site of prior trauma or ...
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Richard J. Wurtman
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S37-S40
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Chest pain of cardiac and noncardiac origin
Abstract: Chest pain is one of the most common symptoms driving patients to a physician's office or the hospital's emergency department. In approximately half of the cases, chest pain is of cardiac or...
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Claude Lenfant
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S41-S46
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Opioids for cancer pain: the challenge of optimizing treatment
Abstract: During 2007, 11.7 million US men and women of all ages suffered from some form of invasive cancer. During their illness, at least 70% (8.2 million) will experience pain sufficiently severe t...
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Gérard E. Plante,
Theodore B. VanItallie
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S47-S52
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Table of Contents
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A1
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