Research Article| Volume 34, ISSUE 6, P571-573, June 1985

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The effect of anabolic steroids on lean body mass: The dose response curve

  • Gilbert B. Forbes
    Address reprint requests to Gilbert B. Forbes, MD, Department of Pediatrics, Box 777, University of Rochester Medical Center, Rochester, NY 14642.
    Department of Pediatrics, University of Rochester Medical Center USA.

    Department of Radiation Biology and Biophysics, University of Rochester Medical Center USA.
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      Data from human subjects given various amounts of anabolic steroids show that the resultant increment in lean body mass (LBM) has the features of a typical dose response curve. Low doses produce a very modest effect, while large doses result in a progressive augmentation of the LBM. Endogenous testosterone production during male adolescence is accompanied by a sex differential in LBM that is comparable to the LBM increment generated by exogenous steroids given to adults.
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