Background: Polyphenols are one of the common most phytochemical found to be present in the plant and their derived product. Eupafolin is flavonoid class phytochemical well known for their antioxidant, anti-inflammatory and anticancer effects is found to be present in the Phyla nodiflora. Objective: Scientific research has proven the biological importance of eupafolin in the medicine for the treatment of numerous biological complications. Methods: Eupafolin have been known for their effectiveness against cervical adenocarcinoma and murine melanoma cells. In order to know the biological potential of eupafolin in the medicine, here in the present investigation numerous scientific data have been collected from various literature sources. All the collected scientific data from different literature sources have been analyzed to know the medicinal properties and pharmacological activities of eupafolin. Molecular mechanistic study has been also performed to know the biological importance of eupafolin in the medicine. Anti- Inflammatory activity of eupafolin in the biological system has been investigated through literature data analysis of various scientific research works. Results: Literature data analysis of various scientific research works revealed the biological potential of eupafolin for their effectiveness against various form of inflammatory disorders. Literature data analysis revealed the biological effects of eupafolin in human lung airway epithelial cells which could be used as therapeutic agent against inflammatory disorders of lung. Data analysis revealed their effectiveness against inflammatory disorders through inhibitory potential against COX-2, IL-6 and TNF-α. Literature data analysis also revealed the effectiveness of eupafolin against inflammatory disorders through inhibitory potential on PGE2 production and COX-2 expression in Hs68 cells. Conclusion: Literature data analysis revealed the biological importance of eupafolin for the prevention and treatment of various form of inflammatory disorders in the medicine and other allied health sectors.
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