Background: Polyphenols are one of the common most phytochemical found to be present
in the plant and their derived product. Eupafolin is flavonoid class phytochemical
well known for their antioxidant, anti-inflammatory and anticancer effects is found
to be present in the Phyla nodiflora. Objective: Scientific research has proven the
biological importance of eupafolin in the medicine for the treatment of numerous biological
complications. Methods: Eupafolin have been known for their effectiveness against
cervical adenocarcinoma and murine melanoma cells. In order to know the biological
potential of eupafolin in the medicine, here in the present investigation numerous
scientific data have been collected from various literature sources. All the collected
scientific data from different literature sources have been analyzed to know the medicinal
properties and pharmacological activities of eupafolin. Molecular mechanistic study
has been also performed to know the biological importance of eupafolin in the medicine.
Anti- Inflammatory activity of eupafolin in the biological system has been investigated
through literature data analysis of various scientific research works. Results: Literature
data analysis of various scientific research works revealed the biological potential
of eupafolin for their effectiveness against various form of inflammatory disorders.
Literature data analysis revealed the biological effects of eupafolin in human lung
airway epithelial cells which could be used as therapeutic agent against inflammatory
disorders of lung. Data analysis revealed their effectiveness against inflammatory
disorders through inhibitory potential against COX-2, IL-6 and TNF-α. Literature data
analysis also revealed the effectiveness of eupafolin against inflammatory disorders
through inhibitory potential on PGE2 production and COX-2 expression in Hs68 cells.
Conclusion: Literature data analysis revealed the biological importance of eupafolin
for the prevention and treatment of various form of inflammatory disorders in the
medicine and other allied health sectors.
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