Inhibitory Activity of Pectolinarin on Melanin Synthesis: Medicinal Importance and Therapeutic Benefit in the Medicine

Background: Plants were used as one of the best source of drugs, food material and general need of human being from very ancient time to till date. Flavonoids are secondary metabolites present in plant sources and scientifically proven for their potential health benefits in the human diet. Pectolinarin is an important phytoconstituents of Cirsium japonicum and Cirsium spp. is widely distributed in Asian and Western countries, China, Japan, including Korea, United States, Canada, and Australia. Objective: Scientific data have been searched and analyzed for the medicinal uses and pharmacological activities of pectolinarin. Methods: In order to know the health beneficial aspects of pectolinarin in the medicine, here in the present investigation numerous scientific data have been searched and analyzed for their medicinal uses and pharmacological activities. Biological importance of pectolinarin in the medicine has been analyzed through literature data analysis of various scientific research works. Biological potential of pectolinarin on melanogenesis have been investigated through scientific data analysis of various research work. Results: Literature data analysis of various scientific research works revealed the biological importance and therapeutic benefit of pectolinarin in the medicine for the treatment of numerous human health disorders. Pharmacological scientific research data analysis revealed the biological potential of pectolinarin in the medicine for their effectiveness against skin disorders. Effects of pectolinarin on melanogenesis were evaluated and revealed that pectolinarin treatment showed less significant inhibitory activity of melanin synthesis.