Background: Adolescents with overweight and obesity are associated with many serious
health complications and increased risk of early-onset of diseases such as diabetes
mellitus, cardiovascular diseases, which causes mortality in the population together
with dyslipidemia, hypertension, and musculoskeletal diseases. The accumulation of
fat characterizes overweight and obesity has been associated with metabolic syndrome
(MetS). Overweight, obesity, MetS are metabolic disorders that cause alterations in
insulin secretion, accompanied by insulin resistance (IR).
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